KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNT5B
All Species:
16.36
Human Site:
S268
Identified Species:
30
UniProt:
Q9H1J7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H1J7
NP_110402.2
359
40323
S268
G
R
L
E
L
V
N
S
R
F
T
Q
P
T
P
Chimpanzee
Pan troglodytes
Q2QLE7
360
40426
E258
T
G
F
T
V
A
N
E
R
F
K
K
P
T
K
Rhesus Macaque
Macaca mulatta
XP_001117880
429
46995
S338
G
R
L
E
L
V
N
S
R
F
T
Q
P
T
P
Dog
Lupus familis
XP_541837
360
40483
S269
G
K
L
V
Q
V
N
S
R
F
N
S
P
T
T
Cat
Felis silvestris
Mouse
Mus musculus
P22726
359
40325
S268
G
K
L
E
L
A
N
S
R
F
N
Q
P
T
P
Rat
Rattus norvegicus
Q9QXQ7
380
42265
S289
G
K
L
V
Q
V
N
S
R
F
N
S
P
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Q07DZ8
361
40096
K259
T
G
F
T
V
A
N
K
R
F
K
K
P
T
K
Chicken
Gallus gallus
P49337
351
38945
S260
K
V
L
V
P
K
N
S
Q
F
K
P
H
T
D
Frog
Xenopus laevis
P33945
360
40662
Q269
N
K
L
E
Q
V
N
Q
R
F
N
P
P
T
G
Zebra Danio
Brachydanio rerio
Q92050
363
41119
N272
G
K
L
E
L
V
N
N
R
F
N
P
P
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397473
422
46971
P331
G
R
L
S
M
R
D
P
R
F
S
L
P
T
A
Nematode Worm
Caenorhab. elegans
P34889
360
40418
E269
L
A
D
E
A
T
K
E
R
K
T
R
A
L
P
Sea Urchin
Strong. purpuratus
XP_779946
415
46408
A324
G
R
L
V
N
S
D
A
R
F
N
K
P
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.5
74.1
80.2
N.A.
94.1
76.8
N.A.
48.7
48.1
83.6
79.6
N.A.
N.A.
52.1
45.5
55.6
Protein Similarity:
100
63.3
78.3
89.1
N.A.
97.7
85
N.A.
63.7
62.9
91.1
89.2
N.A.
N.A.
65.6
66.9
68.6
P-Site Identity:
100
33.3
100
60
N.A.
80
60
N.A.
33.3
33.3
53.3
66.6
N.A.
N.A.
46.6
26.6
46.6
P-Site Similarity:
100
46.6
100
66.6
N.A.
86.6
66.6
N.A.
46.6
40
60
80
N.A.
N.A.
66.6
33.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
24
0
8
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
16
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
47
0
0
0
16
0
0
0
0
0
0
0
% E
% Phe:
0
0
16
0
0
0
0
0
0
93
0
0
0
0
0
% F
% Gly:
62
16
0
0
0
0
0
0
0
0
0
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
39
0
0
0
8
8
8
0
8
24
24
0
0
16
% K
% Leu:
8
0
77
0
31
0
0
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
8
0
77
8
0
0
47
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
8
0
0
0
24
85
0
31
% P
% Gln:
0
0
0
0
24
0
0
8
8
0
0
24
0
0
0
% Q
% Arg:
0
31
0
0
0
8
0
0
93
0
0
8
0
0
8
% R
% Ser:
0
0
0
8
0
8
0
47
0
0
8
16
0
0
0
% S
% Thr:
16
0
0
16
0
8
0
0
0
0
24
0
0
93
16
% T
% Val:
0
8
0
31
16
47
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _